IVF And Miscarriage: Why ‘Knowing Your Numbers’ Matters

Last Updated:July 29, 2025, 18:16 IST

When you are going through IVF, inquire with your doctor about the statistics that are of the greatest importance to your specific situation

Couples who undergo the procedure of IVF (In Vitro Fertilization) hope that in such a way their family will be expanded, but at the same time there are fears and doubts. Miscarriage is one of the most emotionally traumatic process setbacks. Although a woman could miscarry at any pregnancy, the loss may have deeper emotional effects at IVF since every cycle would be associated with much physical, emotional, and financial resources.

Getting to grips with the factors that may cause miscarriage and what might perhaps prevent it involves going deeper into, what many patients do not give much attention to; their numbers. These are levels of hormones, quality of an embryo, chromosomal measurements and measures of uterine health. It is about being informed, it is about being empowered, with regards to saying that you know your numbers.

Dr. Komal Bhadu, Consultant Obstetrics and Gynaecologist, Ruby Hall Clinic, Pune shares all you need to know:

1. Hormonal Balance- The Puzzling Piece of the Jigsaw

Such hormones as AMH (Anti-Mullerian Hormone), FSH (Follicle-Stimulation Hormone), LH (Luteinizing Hormone), progesterone, and estradiol are involved mainly in the quality of eggs, the thickness of endometrium, and embryo implantation. The abnormal levels may decrease the success rate or in some cases will cause miscarriage. These interventions are made possible by regular monitoring, which enables fertility specialists to modify protocols and address imbalances before they can progress.

2. Genetic testing and Embryo Quality

Not every embryo is genetic viable. PGT-A could screen out aneuploid embryos and could determine chromosomally normal embryos, which were more likely to result in successful pregnancy. This is of great significance to the women who are past the age of 35 where their chances of several chromosomal abnormalities are very high hence the risk of miscarriage is high too.

3. The Uterus Conducting Environment

Implantation and maintenance of pregnancy may be influenced by such structural problems as fibroids, polyps, or thin endometrium. Information about the thickness of the uterus lining, the flow patterns of the blood in your body, and anatomical defects is important prior to the embryo transfer. These problems can be identified with the help of imaging devices such as hysteroscopy or sonohysterography.

4. Blood clotting disorders and thyroid Function

Thyroid syndrome and blood clotting disorders are mainly cured with the help of conventional medicine, which consists of the procedure of removal of the thyroid hormones.

Recurrent pregnancy loss is known to be caused by thyroid dysfunction, as well as by such clotting disorders as anti-phospholipid syndrome or thrombophilia not diagnosed previously. These risks can be administered through simple blood tests, and when intervention is made early, the drug can highly benefit the outcome.

5. Individualization of IVF procedures

Each person is distinct and IVF is not a treatment that fits all. Where you monitor the personal reactions made by your body this could be the way you consistently react to the stimulation medication to the manner your lining accumulates so that you as well as your doctor would adjust the protocols to achieve optimal results.

Although miscarriage is in some cases inevitable, the chances of miscarriage can be minimized by knowing your numbers and gaining success in doing the IVF. It will allow you and your fertility considerations to make wiser and individual decisions. It is such a journey that every step is important and in such a journey knowledge is power.

When you are going through IVF, inquire with your doctor about the statistics that are of the greatest importance to your specific situation, and do not back off asking second opinions or additional research. Since there are times when a missed value contributes to the difference between the heartbreak and cradling your baby in your arms.

Swati Chaturvedi

Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she’s a weaver of wit and wisdom in the digital landscape. As a key figure in News18 Engl…Read More

Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she’s a weaver of wit and wisdom in the digital landscape. As a key figure in News18 Engl… Read More

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