Pamela Maldonado
Eric Moody
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Eric Moody
ESPN Writer
- Eric Moody is a writer for fantasy football, men’s and women’s basketball, and sports betting at ESPN. Eric joined ESPN in 2021 after working as a senior fantasy analyst at Pro Football Network. Prior to that, he spent much of his career as a manager at a Fortune 100 financial services company.
Aaron Schatz
CloseAaron Schatz
ESPN Writer
- Aaron Schatz is an NFL analyst for ESPN.com. He has more than 20 years of experience working in NFL analytics and is the creator of the DVOA and DYAR metric. He also serves as the Chief Analytics Officer at FTN Network.
Multiple Authors
Week 10 of the 2026 NFL season is here. The trade deadline came and went, with some surprising moves. QB Kirk Cousins is expected to be the Vikings’ starting quarterback once again, the Chiefs added WR Josh Downs and … RB Jonathan Taylor is still in Indianapolis. A few teams added and others subtracted from their rosters. So, now it’s time to dive back into the games.
We’re here to get you ready for the action. First, our NFL Nation reporters take you inside the locker room with the best thing they heard this week, and ESPN Research provides a key stat to know. Then, analytics writer Aaron Schatz makes a bold prediction for each matchup, fantasy analyst Eric Moody shares fantasy football intel and betting analyst Pamela Maldonado hits betting insights for each contest. We also have Football Power Index (FPI) game projections, and Maldonado, Moody and Schatz all give us final score picks for every game.
Let’s get into the full Week 10 slate, which culminates with a “Monday Night Football” matchup between the Chargers and Ravens on ESPN. (Game times are Sunday unless otherwise noted, and all odds are via DraftKings.)
Jump to a matchup:
NE-DET | BUF-NYJ | CAR-NO
JAX-TEN | KC-ATL | MIA-IND
MIN-GB | HOU-CLE | SEA-LV
LAR-ARI | SF-DAL | PIT-CIN
LAC-BAL
Thursday: WSH-NYG
Bye: CHI, DEN, PHI, TB
What ESPN Analytics says …
9:30 a.m. ET | Fox | DET -2.5 (51.5 O/U)
What we’re hearing on the Patriots: New England is hoping to rebound from a poor defensive effort last week. Coordinator Zak Kuhr said CB Christian Gonzalez had some plays he would want back, but also said there were other plays where he could have been the closest defender because of breakdowns elsewhere. Kuhr acknowledged that very little went right for the defense but thought the unit took steps Wednesday in a spirited practice that featured better communication and connectivity. Kuhr added that the team’s belief in Gonzalez hasn’t wavered. — Mike Reiss
What we’re hearing on the Lions: It’s not every day that the Lions are selected to play in an international game. In fact, it hasn’t happened since 2015, so this is a huge deal for the franchise. WR Amon-Ra St. Brown‘s mother, Miriam, hails from Germany, and he frequently visited the country as a child. This will be a new experience for coach Dan Campbell. “As far as I’ve been across the pond is London, and that was for [a game],” Campbell said. “And I already mentioned, I had an extra pair of underwear and socks and that was it, all right. And a toothbrush, but that’s as far as I’ve been over there.” — Eric Woodyard
Stat to know: Lions QB Jared Goff has had consecutive games with fewer than 200 passing yards for just the second time over the past five seasons. — ESPN Research
Bold prediction: Patriots QB Drake Maye will not throw an interception against the Lions. His 11 interceptions this season are the second most in the league. In general, about 20% of passes defensed turn into interceptions. It’s been a little lower leaguewide this season (16%). For Maye, it has been 34%. So he has been unlucky and shouldn’t be as interception prone going forward. — Schatz
Fantasy nugget: Corey Kiner could be the Patriots’ lead RB against the Lions. Rhamondre Stevenson is expected to miss the game with a knee injury, and TreVeyon Henderson has been ruled out. Kiner has topped 50 rushing yards in three of his past five games despite playing a reserve role. Detroit is a difficult matchup, allowing the second-fewest fantasy points per game to RBs. However, Kiner could see enough volume to be a viable flex option. See Week 10 rankings. — Moody
Betting insight: The Patriots have failed to cover four straight games, tied for the NFL’s longest active streak and their longest since a five-game stretch in 2024. Detroit can keep that going. New England allows 10.6 yards per pass attempt against play-action, which Goff uses constantly. St. Brown can attack the slot, while New England’s battered offensive line leaves Maye dodging pressure. Read more. — Maldonado
Maldonado’s pick: Lions 28, Patriots 23
Moody’s pick: Lions 31, Patriots 24
Schatz’s pick: Patriots 27, Lions 24
FPI prediction: DET, 52.6% (by an average of 0.7 points)
Matchup must-reads: Pats’ Stevenson expected to miss time with knee tendon issue
1 p.m. ET | CBS | BUF -8.5 (50.5 O/U)
What we’re hearing on the Bills: Coming off a short week following “Monday Night Football,” the Bills are still easing LT Dion Dawkins and LG Alec Anderson back into the lineup. But the Bills are plenty aware of Jets coach Aaron Glenn’s aggressive tendencies and standout rookie edge rusher David Bailey‘s recent hot streak. Coach Joe Brady and offensive coordinator Pete Carmichael said they’ll have to be aware of where Bailey lines up every play, and the task of keeping him out of the backfield is urgent: “He’s already a star right now,” Brady says, “but he’s going to be a problem for a lot of years.” — Nick Suss
What we’re hearing on the Jets: The spiraling defense has allowed 32 points per game over the team’s current four-game losing streak. Glenn said he’s “looking at everything” in an attempt to halt the slide. He doesn’t have many personnel options, though it appears that disgruntled edge rusher Will McDonald IV will get more playing time than usual. The Jets have another long interception drought brewing — five straight games without a pick, 15 shy of the league record (set by them just prior to the current five-game slump). — Rich Cimini
Stat to know: Bills RB James Cook III has had 75-plus rushing yards in seven straight games, the longest active streak in the NFL and the longest by a Bills player since Travis Henry in 2003 (eight). — ESPN Research
Bold prediction: Jets WR Garrett Wilson (concussion) will return and set a season high with at least 110 receiving yards. Buffalo currently ranks 27th in DVOA (Defense-adjusted Value Over Average) against WR1s, and Wilson is the Jets’ clear top option. — Schatz
0:35
Will McDonald to get more playing time with the Jets
Fantasy nugget: Jets RB Breece Hall returned from a five-game absence last week and led the Jets’ backfield with 18 touches and 11.7 fantasy points. Before a quad injury, Hall had been the clear lead back on early downs, but he split that work much more evenly with Braelon Allen in Week 9. Allen also played more snaps and ran twice as many routes. Hall could see his snap share increase this week and has a favorable matchup against a Bills defense that has allowed the ninth-most fantasy points per game to RBs. See Week 10 rankings. — Moody
Betting insight: The Jets are 1-7 ATS (against the spread) in division games since the start of last season, worst in the NFL. Their defense has been getting picked apart lately, and now QB Josh Allen gets his turn. Buffalo scores on more than half its possessions. The Jets struggle to finish drives with touchdowns, and trading field goals for touchdowns makes keeping up much harder. Read more. — Maldonado
Maldonado’s pick: Bills 30, Jets 20
Moody’s pick: Bills 34, Jets 20
Schatz’s pick: Bills 24, Jets 16
FPI prediction: BUF, 82.8% (by an average of 9.4 points)
Matchup must-reads: New Bills safety Hooker will be ‘ready to go’ … Why 2-7 Jets preferred to keep roster intact at trade deadline … Jets’ McDonald has ‘earned’ bigger role, coach says
1 p.m. ET | Fox | NO -2.5 (48.5 O/U)
What we’re hearing on the Panthers: Interim defensive coordinator Todd Wash won’t mince words when he talks about his philosophy: “We’re going to load the box. We’re going to stop the run and make you throw to beat us.” Rookie defensive tackle Lee Hunter, a second-round pick, should be a big part of that plan against the Saints. Hunter played only 13 snaps against Denver, but Wash says the lineman’s playing time will be a “major, major point of emphasis” moving forward. — Mike Kaye
What we’re hearing on the Saints: The run game could look different for the second straight week. One week after claiming Audric Estime, the Saints could get Travis Etienne Jr. back from a hamstring injury that has kept him on IR since September. They’ll also have another offensive line shuffle the week after getting LT Kelvin Banks Jr. back, as Erik McCoy (biceps) is out. RG Cesar Ruiz will replace him at center, the position Ruiz played at Michigan. — Katherine Terrell
Stat to know: Saints WR Chris Olave has 734 receiving yards on the season, ranked sixth in the NFL. However, New Orleans is 0-3 when he records 100-plus receiving yards in a game. — ESPN Research
Bold prediction: Panthers WR Tetairoa McMillan will have a 100-yard receiving day. New Orleans ranks 30th in DVOA against opposing WR1s. They allow an opponent-adjusted 87 yards per game to opposing WR1s but only 27 yards per game to opposing WR2s. — Schatz
Fantasy nugget: Panthers QB Bryce Young is coming off a strong performance, finishing with 20.3 fantasy points. His production has been inconsistent, but he’s still a top-12 fantasy QB. Young also has a talented receiving duo in McMillan and Jalen Coker. This week, he faces a Saints defense that allowed Browns backup QB Shedeur Sanders 22.6 fantasy points last week and has given up 17.9 fantasy points per game to QBs this season. See Week 10 rankings. — Moody
Betting insight: The Panthers are 10-2 ATS following a loss since the start of last season, best in the NFL. Young just showed he can get the ball out quickly and also attack downfield. That will come into play against New Orleans’ pass rush. The Saints allow 7.8 yards per attempt, giving Young and McMillan plenty of room to make them pay. Read more. — Maldonado
Maldonado’s pick: Panthers 27, Saints 24
Moody’s pick: Saints 24, Panthers 21
Schatz’s pick: Panthers 27, Saints 23
FPI prediction: NO, 49.9% (by an average of 0.1 points)
Matchup must-reads: Walker keeps ‘analyzing issue’ in protecting QB Young’s blind side … Tyson’s Saints debut showed promise, rookie mistakes … Saints starting C McCoy to miss time with biceps injury, coach says
1 p.m. ET | Fox | JAX -10.5 (46.5 O/U)
What we’re hearing on the Jaguars: There’s still some uncertainty about how much — or if — newly acquired DT Jordan Davis, S Jessie Bates III and DT Davon Godchaux will play Sunday. Godchaux practiced Wednesday and Thursday, but Bates and Davis did not practice Wednesday. Coach Liam Coen said he’ll evaluate their progress late in the week before making any decisions. — Michael DiRocco
What we’re hearing on the Titans: Tennessee has found success running the ball over the past two games, with Tony Pollard going over 100 rushing yards against both the Browns and Bengals. Pollard will look to hit triple figures for the third consecutive game, but the Titans might be without LG Peter Skoronski, who has missed practice time this week because of a hamstring injury. This week will be a bigger challenge against the Jaguars, who have allowed the fifth-fewest rushing yards per game (89.3) but gave up 172 yards on the ground last week. — Turron Davenport
Stat to know: The Titans have grabbed multiple takeaways in three straight games, their longest streak since 2021 (three straight). A fourth straight game would be their longest single-season streak since 2008 (five). — ESPN Research
Bold prediction: Jaguars edge rusher Josh Hines-Allen will get a sack. He has only two sacks this season, but he’ll get at least one more against Tennessee LT Dan Moore Jr., who ranks 55th out of 66 qualified tackles in pass block win rate. — Schatz
2:53
Andrew Hawkins: The Jaguars are the ‘most complete team in the AFC’
Fantasy nugget: Jaguars QB Trevor Lawrence and WR Parker Washington weren’t asked to do much in Jacksonville’s blowout win over Baltimore, finishing with 13.5 and 14.1 fantasy points, respectively. Both have a great opportunity to bounce back. The Titans have allowed the eighth-most fantasy points per game to QBs and the most to WRs. Lawrence has also averaged 23.4 fantasy points in his past four games against Tennessee. See Week 10 rankings. — Moody
Betting insight: The Jaguars are 3-0 ATS as favorites of 10 or more points since the start of last season, tied for the NFL’s best record. Tennessee keeps giving up big passing plays, and Lawrence has the receivers to exploit that. Jacksonville has jumped on teams early, while Tennessee keeps falling behind. That could leave QB Cam Ward playing catch-up. Read more. — Maldonado
Maldonado’s pick: Jaguars 31, Titans 17
Moody’s pick: Jaguars 30, Titans 17
Schatz’s pick: Jaguars 27, Titans 17
FPI prediction: JAX, 83.9% (by an average of 10.1 points)
Matchup must-reads: Jaguars trade deadline takeaways, from ‘F them picks’ to BTJ staying … Where does QB Ward stand coming out of the bye?
1 p.m. ET | CBS | KC -3 (46.5 O/U)
What we’re hearing on the Chiefs: WR Josh Downs is expected to make his debut with the Chiefs following Tuesday’s trade from the Colts. Before his first practice Wednesday, Downs explained how excited he is to be playing with QB Patrick Mahomes. “I mean, who wouldn’t love playing with a quarterback of his caliber? You can’t really put it into words. I’ve been following Mahomes for years. When people are playing in college, that’s the quarterback that everybody is like, ‘I want to go play with Mahomes.’ It’s truly a blessing. He makes plays in the pocket but out of the pocket as well. Having that scramble aspect is really big, and he makes a lot of plays out of that.” — Nate Taylor
What we’re hearing on the Falcons: The Chiefs are middle of the pack in blitz rate and QB pressure rate, but don’t be surprised if they dial things up against the Falcons like they did in Week 9, when they had a 50% pressure rate. Atlanta’s Michael Penix Jr. completes a league-low 34% when pressured, which is the second lowest by a qualified QB in a season since at least 2018, per NFL Next Gen Stats. The Falcons have yet to figure out how to make blitzing teams pay, and RB Bijan Robinson has just one touchdown since Week 4. — Marc Raimondi
Stat to know: The Chiefs’ offense has had five games with 150 or more rushing yards, which is tied for the most in a season under coach Andy Reid. — ESPN Research
Bold prediction: Robinson will have more than 50 yards as a receiver. The Chiefs rank 28th in DVOA against RBs as receivers, allowing an (opponent-adjusted) average of 40 yards per game, and Robinson is about as good a receiving back as there is. — Schatz
Fantasy nugget: Falcons TE Kyle Pitts Sr. hasn’t reached 25 receiving yards in any of his past three games, despite seeing at least five targets in each. Atlanta’s offense has struggled during that stretch, averaging the fifth-fewest total yards per game. Pitts has a more favorable matchup against the Chiefs, who have allowed the sixth-most fantasy points per game to TEs while giving up the second fewest to WRs. That could lead to more opportunities for Pitts in the passing game and give him a chance to bounce back. See Week 10 rankings. — Moody
Betting insight: The Chiefs are 5-13 ATS in November over the past five seasons, worst in the NFL. Kansas City’s defense allows 2.18 points per drive on the road, compared with 1.32 at home. Penix has played better at home, too. If Robinson can stay consistent, the Falcons can make this a competitive fourth-quarter game. Read more. — Maldonado
Maldonado’s pick: Chiefs 24, Falcons 23
Moody’s pick: Chiefs 27, Falcons 20
Schatz’s pick: Chiefs 27, Falcons 24
FPI prediction: KC, 78.1% (by an average of 7.8 points)
Matchup must-reads: Chiefs sticking with struggling Butker as kicker … Falcons trade C Neuzil to Ravens for G Vorhees, pick … How Downs fits with Mahomes and the Chiefs’ offense
1 p.m. ET | CBS | IND -3.5 (38.5 O/U)
What we’re hearing on the Dolphins: QB Kyle McCord will start for at least the next four weeks while Malik Willis is sidelined with a groin injury — and the first snaps McCord takes Sunday will be his first with the first-team offense in a game situation. Miami traded for McCord in August after the preseason ended, but the team feels comfortable with his grasp of the playbook, despite limited reps. McCord said he prides himself on being able to run anything OC Bobby Slowik wants to call. At the same time, coach Jeff Hafley said the Dolphins don’t have time to install a new offense, so there will be a learning curve for all parties as they figure out what works. — Marcel Louis-Jacques
What we’re hearing on the Colts: Indianapolis completed its midseason roster overhaul by trading WRs Josh Downs and Keenan Allen, and that has left a shell of a group remaining at the position. The Colts receivers who will take the field Sunday have a combined 27 receptions and 375 yards. Downs and Allen had a combined 73 catches for 705 yards but now will be playing for the Chiefs and 49ers, respectively. New slot receiver Anthony Gould, who replaces Downs, has four career catches and has played only two offensive snaps this season. — Stephen Holder
Stat to know: The Colts have scored 23 or fewer points in five straight games. A sixth straight game would tie their second-longest single-season streak in the past 30 seasons (11 straight in 2017, six consecutive in 2011). — ESPN Research
Bold prediction: Chop Robinson will have a pair of sacks. The Dolphins’ edge rusher is the surprising midseason leader in pass rush win rate (32.7%), while the Colts have an average (13th) pass-blocking offensive line. — Schatz
0:57
Kyle McCord prepares for first career start
Fantasy nugget: The Dolphins could lean more heavily on Ollie Gordon II and the running game since Willis is on IR. Gordon hasn’t scored double-digit fantasy points since Week 7, but he has had at least 17 touches in each of his past three games. That workload is encouraging heading into a favorable matchup against a defense that has allowed the eighth-most fantasy points per game to RBs. See Week 10 rankings. — Moody
Betting insight: The Colts are this season’s first favorite with a losing streak of at least five games. Those teams went 1-3 ATS last season. Indianapolis can buck that. Miami is starting McCord, and losing Willis removes any scrambling threat from the position. The Dolphins allow 8.1 yards per pass attempt, giving Daniel Jones a chance to finally get something going. Read more. — Maldonado
Maldonado’s pick: Colts 23, Dolphins 17
Moody’s pick: Colts 23, Dolphins 13
Schatz’s pick: Colts 23, Dolphins 16
FPI prediction: IND, 81.9% (by an average of 9.2 points)
Matchup must-reads: Dolphins hopeful QB Willis will be back this season … RB Taylor focused on being leader for Colts with trade deadline drama over … Dolphins captain Sieler out for rest of season with ruptured biceps … Taylor, QB Jones remain with Colts as trade deadline passes
1 p.m. ET | Fox | GB -3 (42.5 O/U)
What we’re hearing on the Vikings: The Vikings celebrated the acquisition of QB Kirk Cousins this week, hoping he can pick up where he left off when he last played for them in 2023. (His last game wearing their uniform was, coincidentally, at Lambeau Field.) Specific to Sunday, can they protect Cousins? Vikings QBs this season have been pressured an NFL-high 46.9% of the time. Some of that has been the result of QB indecision, but the scheme has also struggled to adjust to stunts and keep pass rushers out of the backfield. — Kevin Seifert
What we’re hearing on the Packers: The Packers aren’t ignoring their 39-22 loss to the Vikings to open the season, but they’re not dwelling on it in advance of their rematch, either. The Packers’ offensive line was a mess that day, and there’s no worse place to have offensive line issues than at the raucous U.S. Bank Stadium. “You might as well throw Week 1 out the window in most instances,” coach Matt LaFleur said. “There’s a lot of craziness that goes on — unscouted looks and you just never know what you’re going to get. I do think it’s going to be helpful. That place is such a hard place to play, and it caused us some issues where we didn’t have everybody on the same page, especially from an offensive standpoint.” — Rob Demovsky
Stat to know: The Packers’ 19 takeaways are the second most in the NFL (Buccaneers, 21). — ESPN Research
Bold prediction: Vikings kick returner Myles Price will return at least one kickoff past the 50, maybe for a touchdown. The Packers are currently 30th in my net kickoff value metric, while the Vikings rank fourth in kick return value. — Schatz
Fantasy nugget: The Vikings have scored only 11 offensive touchdowns in eight games, tied with the Chargers for the fewest in the league. Cousins’ return could help turn things around. He spent two seasons playing under coach Kevin O’Connell and already has an established connection with Justin Jefferson and Jordan Addison. There could be an adjustment period, but both WRs belong in lineups against a Packers defense that has allowed the sixth-most fantasy points per game to the position. See Week 10 rankings. — Moody
Betting insight: The under is 6-1 in Vikings games, 4-0 on the road. That’s without having an efficient QB. Cousins helps, but him joining midweek brings adjustments. Green Bay defends deep throws well and limits touchdowns off play-action, a big part of Cousins’ success. Both offenses have problems to work around here. Minnesota’s pressure can trouble QB Jordan Love behind a banged-up line. Read more. — Maldonado
Maldonado’s pick: Packers 20, Vikings 17
Moody’s pick: Packers 24, Vikings 20
Schatz’s pick: Vikings 24, Packers 20
FPI prediction: GB, 55.7% (by an average of 1.4 points)
Matchup must-reads: What the Cousins trade means for the Vikings and the Raiders … Does Packers’ Watson + Golden = 3,000 yards? … Cousins says call with O’Connell convinced him to OK Vikings trade
1 p.m. ET | Fox | HOU -4.5 (40.5 O/U)
What we’re hearing on the Texans: The Texans have some RB questions. Woody Marks (knee) didn’t finish practice Wednesday and didn’t participate Thursday, while David Montgomery (groin) hasn’t played since Week 5. But Montgomery did practice Thursday, so that’s promising. Rain is expected in Cleveland, so while Houston’s passing attack has been humming, it’ll likely need the ground game to supplement the offense. — DJ Bien-Aime
What we’re hearing on the Browns: The Browns’ defense might face its toughest test to date against QB C.J. Stroud. Cleveland plays Cover 1 on a league-high 39.8% of passing plays, but Stroud has feasted on that coverage; his 8.3 yards per attempt against Cover 1 are eighth most among qualified passers. “He’s been slinging the ball all around the field, getting those guys the ball and just a really good team,” CB Denzel Ward said. “So we’re definitely going to have our work cut out for us this week, and I think we’re up for the challenge, though.” — Daniel Oyefusi
Stat to know: The Browns have scored a touchdown on 39% of red zone possessions (last in the NFL). — ESPN Research
Bold prediction: Browns QB Deshaun Watson will be sacked by both of Houston’s edge rushers (Will Anderson Jr. and Danielle Hunter). Watson has the worst adjusted sack rate (12.0%) of any regular starting QB in the NFL this season. — Schatz
1:00
C.J. Stroud has been dialed in lately
Fantasy nugget: Backup QB Shedeur Sanders gave Cleveland’s passing game a lift last week. WR KC Concepcion finished with 85 yards and a touchdown. Denzel Boston drew a team-high seven targets and finished with a career-high 98 yards. Deshaun Watson should be back in the lineup, but the receiver matchup against Houston is favorable, with the Texans allowing the second-most fantasy points per game to WRs. Both rookies are worth considering as flex options. See Week 10 rankings. — Moody
Betting insight: The Texans are 9-3 ATS against the Browns since 2005. Cleveland’s protection problems give Houston another opening. The Browns allow sacks at the league’s highest rate, while Houston has the second-highest sack rate. That means stalled drives for an offense already struggling to finish near the goal line. Stroud has also handled man coverage without throwing an interception. Read more. — Maldonado
Maldonado’s pick: Texans 24, Browns 16
Moody’s pick: Texans 24, Browns 13
Schatz’s pick: Texans 24, Browns 17
FPI prediction: HOU, 76.1% (by an average of 7.3 points)
Matchup must-reads: A ‘confident’ QB Stroud soaks in five-TD day against Chargers … Browns’ Monken: Watson over Sanders QB decision based on ‘full body of work’
4:05 p.m. ET | CBS | SEA -6.5 (40.5 O/U)
What we’re hearing on the Seahawks: Nick Emmanwori‘s 26 coverage snaps last week were tied for his most this season. Several of them came against TE Trey McBride, who had seven catches but none on Seattle’s second-year DB. If the Seahawks deploy Emmanwori similarly on Sunday, it could be a popcorn-worthy matchup with another All-Pro TE in Brock Bowers. “Nick can run with anybody as we know, but [he also has] the ability to stay connected at the top of routes,” coach Mike Macdonald said. “The best tight ends are able to use physicality to create separation, and Nick’s able to fight fire with fire on that front or be able to absorb … some of those tricks of the trade, so to speak, and still stay connected.” — Brady Henderson
What we’re hearing on the Raiders: The Raiders’ secondary will have its hands full against WR Jaxon Smith-Njigba. The star pass catcher has totaled 1,036 receiving yards and has recorded at least 100 yards in seven of nine games played. Las Vegas doesn’t like to have its CBs shadow defenders, meaning Eric Stokes will not be matched up with Smith-Njigba the whole game. That said, Darien Porter and rookies Jermod McCoy and Hezekiah Masses should get their fair share of opportunities against the reigning Offensive Player of the Year. The Raiders have allowed 234.2 passing yards per game (26th). — Ryan McFadden
Stat to know: Bowers has had seven straight games with 70 receiving yards, which is tied for the longest streak by a TE in history (Rob Gronkowski). — ESPN Research
Bold prediction: Seahawks RBs Jadarian Price and Zach Charbonnet will each run for at least 70 yards. The Raiders are dead last in run defense DVOA and also give up a ton of long highlight runs. They are 31st in second-level yards per carry (yardage given up 5-10 yards past the line of scrimmage) and 29th in open-field yards per carry (yardage given up 11 or more yards past the line of scrimmage). — Schatz
Fantasy nugget: Charbonnet looks like the Seahawks’ lead back again, but Price remains involved. Charbonnet led Seattle in carries last week, rushing 16 times for 77 yards. Price had 13 touches, including four catches for 54 yards, and outscored Charbonnet 11.8 to 9.6 in fantasy. Both have flex appeal against the Raiders, who have allowed the second-most fantasy points per game to RBs and a league-worst 5.21 yards per carry. Charbonnet has the edge in rushing volume, while Price offers more receiving upside. See Week 10 rankings. — Moody
Betting insight: The over has hit in seven straight Raiders games, but QB Fernando Mendoza‘s first start comes against a Seattle defense allowing a league-low 5.5 yards per pass attempt. Las Vegas can’t lean on a run game averaging 2.9 yards per carry. With Drew Lock dealing with elbow and oblique injuries, Seattle can keep things simple and run against this Raiders’ defense. Read more. — Maldonado
Maldonado’s pick: Seahawks 24, Raiders 16
Moody’s pick: Seahawks 27, Raiders 17
Schatz’s pick: Seahawks 24, Raiders 17
FPI prediction: SEA, 73.9% (by an average of 6.4 points)
Matchup must-reads: Seahawks to start Lock, give Darnold more time to heal … Mendoza relishes ‘once-in-a-lifetime’ opportunity as Raiders’ QB1 … Mendoza and the Raiders’ sit-and-learn plan: Is he ready to start?
4:05 p.m. ET | CBS | LAR -9.5 (39.5 O/U)
What we’re hearing on the Rams: In Week 9, Aaron Donald and Myles Garrett had a 17% sack and 44% pressure rate when they were on the field together, according to ESPN Research. The Cardinals have the second-worst pass block win rate (34.9%) in the NFL. They’ll be facing rookie QB Carson Beck, who will make his first career start. Garrett and Donald have combined for 6.5 sacks and 10 pressures across six games against QBs making their first career start. — Sarah Barshop
What we’re hearing on the Cardinals: It’s Carson Beck time. The rookie will make his NFL debut Sunday but didn’t seem too fazed when he was asked about facing Garrett and Donald. “You look at their defense just as a whole, they’re super talented,” Beck said. He went on to praise the entire unit, not mentioning Garrett or Donald by name. “What they’re able to do on defense, it causes problems for offenses, and it’s definitely going to be a challenge for us,” Beck said. “I think the biggest thing is watching the film, seeing what we want to do, and then ultimately trying to go out there and execute our plan.” — Josh Weinfuss
Stat to know: Cardinals RB Tyler Allgeier has two rushing touchdowns, tied for the third fewest among 28 players with 80 rushes. (Ashton Jeanty and Chase Brown have one each.) — ESPN Research
Bold prediction: Garrett will have not one, not two, but three sacks. Arizona tackles Elijah Wilkinson and Jayden Williams rank 64th and 66th out of 66 tackles in pass block win rate, and rookie QBs are not known for their pocket awareness. — Schatz
1:11
Cardinals coach: Carson Beck’s been a pro since he’s been here
Fantasy nugget: Matthew Stafford and the Rams will be without their top two WRs, Puka Nacua (knee/toe) and Davante Adams (hamstring), in the near future. That could force Los Angeles to lean more heavily on its running game, especially as a huge favorite. Arizona has allowed 20.9 fantasy points per game to RBs. Kyren Williams remains a must-start, while Blake Corum deserves flex consideration after rushing for 58 yards and a touchdown on 11 carries last week. See Week 10 rankings. — Moody
Betting insight: Arizona has three wins as an underdog of seven or more points this season, the only team with multiple. Another win is asking a lot, but hanging around is doable. Stafford is missing Nacua and Adams, and the Rams scored only 16 points in their first meeting with both receivers available. Their depleted passing game could keep this one close again. Read more. — Maldonado
Maldonado’s pick: Rams 23, Cardinals 16
Moody’s pick: Rams 27, Cardinals 17
Schatz’s pick: Rams 27, Cardinals 20
FPI prediction: LAR, 87.4% (by an average of 11.5 points)
Matchup must-reads: McVay: Rams optimistic WR Adams will return ‘sooner than later’ … Cardinals to start rookie QB Beck
4:25 p.m. ET | Fox | SF -3.5 (55.5 O/U)
What we’re hearing on the 49ers: San Francisco is embarking on its second 10-plus day trip of the season, as the 49ers head to Dallas before spending next week in Colorado Springs for altitude acclimation before meeting the Vikings in Mexico City. It’s a lot of time away from home, but LB Fred Warner said it’s easy to keep the focus on the Cowboys given the history the two franchises share and what another win can do for San Francisco’s hopes to land the NFC’s top seed. “I love the energy around the old rivalry of Dallas versus the Niners,” Warner said. “In my mind, this is the Super Bowl this week.” — Nick Wagoner
What we’re hearing on the Cowboys: Dallas is still trying to earn a signature win in 2026. If the Cowboys can beat the 49ers, then perhaps they can turn a corner and put pressure on the Giants in the NFC East. The Cowboys have lost their only game to a team with a winning record this season (Green Bay) and are 2-4-1 overall against winning teams under coach Brian Schottenheimer. It would be a signature win for a team in need of one. “Those are big, big, big momentum boosts,” Schottenheimer said. “One that we’re preparing very diligently for.” — Todd Archer
Stat to know: The Cowboys’ franchise-record 16 straight games allowing 20-plus points is the NFL’s longest active streak. It’s also the longest streak by any team since the 2019-21 Jaguars (25 straight). — ESPN Research
Bold prediction: The 49ers’ Brock Purdy will scramble for a touchdown. QBs have scrambled a league-high 24 times against the Cowboys this season for an average of 7.0 yards per carry. — Schatz
Fantasy nugget: 49ers RB Kaelon Black has had at least 11 carries in each of his past two games, averaging 5.8 yards per carry over that stretch. Christian McCaffrey remains the clear lead back, but he’s 30 and handled 450 touches last season, including the playoffs. That’s another reason Black should be rostered in more fantasy leagues as insurance. He should continue to see opportunities against a Cowboys defense that has allowed the fourth-most fantasy points per game to RBs this season. See Week 10 rankings. — Moody
Betting insight: The over has hit in each of the past four meetings between San Francisco and Dallas. The 49ers lead the league in yards per possession, while Dallas allows the most. McCaffrey can punish a defense allowing 5 yards per carry. QB Dak Prescott has room to answer, especially if San Francisco’s injured CBs (Deommodore Lenoir, Renardo Green and Upton Stout) cannot go. Both offenses can contribute here. Read more. — Maldonado
Maldonado’s pick: 49ers 31, Cowboys 28
Moody’s pick: 49ers 31, Cowboys 27
Schatz’s pick: 49ers 28, Cowboys 27
FPI prediction: SF, 63.7% (by an average of 3.5 points)
Matchup must-reads: Veteran WR Allen feeling energized by trade to 49ers … Cowboys rave about Williams a year after trade deadline deal … The key behind 49ers’ 7-1 start? Big contributions from the team’s youth
8:20 p.m. ET | NBC | CIN -3.5 (49.5 O/U)
What we’re hearing on the Steelers: Though the Steelers have 26 sacks this season, including eight in their past outing, the pass rush sacked QB Joe Burrow just once in Week 3, something that was largely a by-product of Burrow getting the ball out quickly. That could very well be the Bengals’ formula again this week, but DT Cameron Heyward said the key for the Steelers’ front is to stay patient and capitalize when the opportunities arise. And often that will mean trying to get pressure to give the secondary as much help as possible against the Bengals’ receiving threats. “Going into this game, we’re not going to have as many shots,” he said. “But when we get them, we got to make them count.” — Brooke Pryor
What we’re hearing on the Bengals: Don’t do too much. That’s the best approach for Cincinnati when it comes to trying to get RB Jaylen Warren on the ground. LB Demetrius Knight Jr. said being in the right gap and not trying to take on too many assignments during a play will be crucial to keeping Warren from having an explosive day. — Ben Baby
Stat to know: Steelers edge rusher T.J. Watt has 12 sacks in 13 career games against Cincinnati, his fewest versus any AFC North opponent (17 vs. Cleveland, 16 vs. Baltimore). — ESPN Research
Bold prediction: Bengals RB Chase Brown will score a receiving touchdown. The Steelers lead the NFL in run defense DVOA, but after adjusting for opponent quality, no defense gives up more receiving yards per game to RBs. — Schatz
2:23
Who has the edge in Steelers-Bengals?
Fantasy nugget: Steelers TE Pat Freiermuth has averaged 9.9 fantasy points per game and has scored double digits in three of his past five games. He still shares snaps and targets with Darnell Washington, but the Week 10 matchup is favorable against a Bengals defense that has allowed the ninth-most fantasy points per game to TEs. See Week 10 rankings. — Moody
Betting insight: The Bengals are 1-6 ATS against the Steelers since 2023. This matchup gives Pittsburgh a way to hang around. Warren already piled up 176 total yards against Cincinnati, which has allowed 11 runs of at least 20 yards. QB Aaron Rodgers can also attack underneath with WR Germie Bernard and Washington against a defense that struggles inside the numbers. Read more. — Maldonado
Maldonado’s pick: Steelers 27, Bengals 24
Moody’s pick: Bengals 28, Steelers 24
Schatz’s pick: Bengals 28, Steelers 20
FPI prediction: CIN, 70.4% (by an average of 5.4 points)
Matchup must-reads: Mike Tomlin: ‘Excited’ about broadcast role, hasn’t considered coaching return … Bengals’ Zac Taylor apologizes for failed trade with Eagles: ‘It was on our end’
Monday, 8:15 p.m. ET | ESPN | BAL -4.5 (38.5 O/U)
What we’re hearing on the Chargers: “Win the next game. Win this game and get on the roll. That’s our goal,” coach Jim Harbaugh said this week. The Chargers trudge along in a winless season in which nothing appears to be going their way, including an agreed-to trade that would have sent LB Daiyan Henley to the Broncos in exchange for future fourth- and fifth-round picks. But the trade unexpectedly fell through, so Henley returns to a squad that’s neither contending nor rebuilding ahead of a cross-country trip to Baltimore, where he’ll anchor a defense facing a Ravens squad starting a fourth QB in Jacoby Brissett. — Lindsey Thiry
What we’re hearing on the Ravens: The Ravens have allowed the third-most points over the past three weeks (34.7 per game), but they’re facing a Chargers offense that has struggled equally. Los Angeles ranks last in scoring (15.1) and touchdowns (11). Coach Jesse Minter, who spent the previous two seasons as the Chargers’ DC, believes QB Justin Herbert hasn’t been as consistent because of the drastic change in offensive systems. “I see flashes, and I see potential,” Minter said. “I certainly know what he’s capable of and respect him.” — Jamison Hensley
Stat to know: The Chargers’ defense has allowed 21 points in all eight games (tied with the Cowboys for most in the NFL). The Ravens’ defense has allowed 21 or more in seven games (tied with the Raiders for third most). — ESPN Research
Bold prediction: Ravens edge rusher Trey Hendrickson will sack Herbert at least once. Hendrickson has been a disappointment with only two sacks for the Ravens so far, but he still ranks fourth among edge rushers in pass rush win rate. — Schatz
Fantasy nugget: Ravens RB Derrick Henry has averaged only 7.6 fantasy points over his past four games, despite seeing 16.5 touches per game. Brissett won’t have much time to learn the Ravens’ playbook, but the offense should be more functional with him. That could help Henry, especially if Baltimore leans more heavily on its running game against a Chargers defense that has allowed 22.6 fantasy points per game to RBs this season. See Week 10 rankings. — Moody
Betting insight: The Ravens have failed to cover eight straight home games dating to last season, their longest streak in franchise history. Brissett joins an offense struggling to move the ball, and Henry is averaging only 3.5 yards per carry without Lamar Jackson (thumb). Herbert gets chances against a defense allowing 7.6 yards per attempt, keeping Los Angeles within reach for its first ATS cover this season. Read more. — Maldonado
Maldonado’s pick: Ravens 20, Chargers 17
Moody’s pick: Ravens 23, Chargers 16
Schatz’s pick: Ravens 20, Chargers 17
FPI prediction: LAC, 54.4% (by an average of 1.2 points)
Matchup must-reads: Harbaugh frustrated with Broncos after nixed Henley trade … Source: Ravens, now on third kicker, sign journeyman Patterson … Sources: Jackson told Ravens teammates he plans to return this season
