Selma Blairhas shared a health update following her Multiple Sclerosis diagnosis.
The 53-year-old actor was diagnosed with the autoimmune disease, which affects the brain and spinal cord, in 2018. Symptoms can include numbness or tingling, dizziness, loss of coordination or difficulty walking, according to the Mayo Clinic.
Blair made an appearance on Tuesday’s episode of Today and shared that, despite feeling “tired a lot,” she is doing “really well.”
“That’s just the truth of it. So I don’t want any of the people with chronic illness to feel like, ‘How does she do that?’ I’m like, ‘Oh no, no, that’s makeup and happiness. There’s fatigue,’” she shared. “But I am, really, really well. I am relapse-free. I’m happy.”
An MS relapse is described as the occurrence of new MS symptoms or the worsening of old ones for at least 24 hours when it’s been 30 days since their last relapse, according to the National Multiple Sclerosis Society.
During her appearance on Today, Blair noted that she’s “ready” to get back to work next month, which is when she’ll be filming Ethan Almighty – Ethan’s Law. The film is based on the viral true story of Jeff Callaway, who adopted a severely neglected dog, Ethan, after he was found in a Kentucky Humane Society parking lot.
In the new movie, Blair plays Claire Patterson, who is struggling with questions of faith and a personal loss, but has a powerful change in perspective when she meets Ethan.
The Cruel Intentions star has previously opened up about being in a good place amid her MS. She reiterated to People in April 2025 that she was “doing amazingly well” and “relapse-free.”
“I’ve been feeling great for about a year,” she told the publication at the time. “But I am finally well enough to really, genuinely … I always try and feel my best, but now that I actually have stamina and energy and getting out and going out isn’t so scary.”
The actor has also reflected on receiving her MS diagnosis. She told British Vogue in 2023 that her doctor initially advised her to keep her diagnosis a secret.
“The advice was to keep it to myself. That work ‘wouldn’t have to know.’ People didn’t feel safe sharing that stuff,” she told the publication.
Blair detailed some of the physical challenges she faced throughout her childhood, decades before being diagnosed with MS. At the age of seven, she told Vogue, she lost use of her right eye, left leg, and her bladder.
While she didn’t realize it at the time, the symptoms she had were a result of juvenile MS. Her then-doctor didn’t take her health struggles seriously, so her condition as a child went undiagnosed.
“If you’re a boy with those symptoms, you get an MRI. If you’re a girl, you’re called ‘crazy,’” the Legally Blonde star said.
